Macrophages are white blood cells that accumulate in tumors, where they aid cancer progression. Now scientists have identified a surface protein found only on the macrophages residing in tumors, exposing a target for precise tumor treatments.
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Paralyzing damage in spinal cord injury is often caused by the zealous immune response to the injury. NIBIB-funded engineers have developed nanoparticles that lure immune cells away from the spinal cord, allowing regeneration that restored spinal cord function in mice.
Scientists have taken a common, yet laborious lab test and redesigned it to be performed in small 3D printed pipette tips used to measure and transfer fluids in the laboratory.
Researchers have created 3D printed customized implants that may boost the power of cell-based therapies for repairing injured spinal cords.
Bioengineers have developed a 3D printing technique that creates the interacting networks for transport of air, blood, and other bodily fluids—a major step toward 3D printed replacement organs.
NIBIB-funded researchers used photoacoustic imaging for rapid measurement of metabolic rate of individual cells from breast tumors—information that can help guide treatment strategies.
NIBIB researchers have designed a nanoparticle that generates radiation-induced oxygen free radicals in the low-oxygen center of tumors, dramatically increasing tumor destruction.
An NIH-funded team has developed a technique called implosion fabrication to build impressively small and intricate components on the nanoscale.
Researchers funded by NIBIB have designed neuron-like probes that can be implanted and remain viable for long-term use to study and treat the brain.
NIBIB-funded engineers are designing aortic heart valve replacements made of polymers rather than animal heart tissues. The goal is to optimize valve performance and enable increased use of a minimally-invasive method for valve replacement over open heart surgery.
Researchers are making amazing progress in developing new imaging approaches that provide us with jaw-dropping views of a wide range of biological systems, including the incredibly complex neural networks within the mammalian brain.