The National Institutes of Health has launched an ambitious effort to use artificial intelligence, computation, and medical imaging to enable early disease detection, inform successful treatment strategies, and predict individual disease outcomes of COVID-19.
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A new technique funded by NIBIB and developed by University of Minnesota researchers allows 3D printing of hydrogel-based sensors directly on the surface of organs, such as lungs—even as they expand and contract. The technology was developed to support robot-assisted medical treatments.
NIBIB-funded researchers at Stanford University have created an artificial neural network that analyzes lung CT scans to provide information about lung cancer severity that can guide treatment options.
Understanding the source and network of signals as the brain functions is a central goal of brain research. Now, Carnegie Mellon engineers have created a system for high-density EEG imaging of the origin and path of normal and abnormal brain signals.
To counter drug resistance, scientists must engineer new drugs to kill mutated cancer cells or pathogens. Now, Penn State engineers have developed a new approach for predicting which mutation has expanded the most in a population and should be targeted to design the most effective new drug.
Bioengineers have created a blood-drawing robot that performed as well or better than technicians. The device could increase blood draw success from difficult- to-find veins and allow healthcare workers more time to treat patients.
Bioengineers have combined standard microscopy, infrared light, and artificial intelligence to assemble digital biopsies that identify important molecular characteristics of cancer biopsy samples.
Bioengineers have created a 3D-printed scaffold designed to regenerate complex tissues composed of multiple layers of cells with different biological and mechanical properties.
Most medicines work by binding to and blocking the effect of disease-causing molecules. Now, to accelerate the identification of potential new medicines, bioengineers have created a computer model that mimics the way molecules bind.
Promising intracellular protein-based therapeutics have been of limited use due to the difficulty of delivery into diseased cells. Now bioengineers have developed nanoparticles that can deliver these therapeutics to their targets—avoiding degradation and toxic interactions with healthy tissues.
Neurologists have observed reduced neural activity during non-rapid eye movement sleep (NREM). Now MRI imaging during NREM reveals an exchange between brain blood and cerebrospinal fluid that may function to remove neurotoxic waste products.
The novel approach better mimics the tumor environment in patients. Made with extracellular matrix (ECM) from pig brains and seeded with tumors from patients, the system is revealing tumor/ECM interactions that aid tumor growth, providing potential targets for new therapies.
Mothers and children in low resource communities often suffer from micronutrient deficiencies. Now NIBIB-funded researchers have developed a system that can be used for tests to rapidly identify blood micronutrient levels in remote areas with limited healthcare infrastructure.
The annual awards ceremony at the National Academy of Engineering was highly unusual in that, of the 12 broad engineering categories represented at NAE – from chemical to mechanical and civil to electrical – three 2019 NAE awards were in biomedical engineering.
Women undergoing treatment for ovarian cancer are checked for tumor cells that may have spread to surrounding tissues, but current technologies miss very small metastatic areas. Now a laser microscopy technique is able to identify these regions with great accuracy.