To provide better diagnosis and treatment of chronic liver diseases, researchers are working to use non-invasive MRI to detect and quantify liver fibrosis throughout the entire organ, which would enable earlier detection and the ability to monitor disease progression as well as the effects of treatment over time.
More by Jessica Meade
With an eye toward early disease detection, synthetic biology engineers at the University of Wisconsin have designed and engineered bacteria that find and detect fragments of DNA shed from infectious pathogens.
Researchers built a motor that could operate a robotic device made from non-magnetic materials and was powered by the magnetic field produced by the MRI.
Researchers are developing new MRI contrast agents that are activated in low oxygen environments enabling improved diagnosis and treatment of hypoxic tumors as well as other diseases.
Scientists at Duke University supported with funds from NIBIB have developed an ultra-fast photoacoustic imaging system capable of visualizing functional and molecular changes in the brain related to major brain disorders.
NIBIB researchers and their collaborators introduce several novel image restoration strategies that create sharp images with significantly reduced processing time and computing power.
The NIH announced the winners of the DEBUT Challenge with prizes totaling $130,000
A research team developed a microscope that combines rapid high- and low-power light-sheet microscopy with an open top design that allows for rapid imaging of a wide range of sample types
Improvements in brain sensing technologies have allowed clinicians to perform increasingly complex surgeries and enabled researchers to map the signals of the brain that control feeling, movement, and thought.
Photoacoustic (PA) imaging is a non-ionizing imaging platform that combines light and ultrasound to safely image structures and molecules in the body. Researchers have now designed a nanoparticle-based PA contrast agent that targeted and significantly enhanced photoacoustic images of ovarian tumors in a mouse model.
Bacterial infections are the leading cause of disease and death worldwide; an ongoing public health problem exacerbated by slow or inaccurate diagnostics. Now NIBIB-funded scientists have engineered an inexpensive, paper-based test that can rapidly identify multiple types of bacteria.
Scientists have developed a single point-of-care assay that identifies malaria, typhoid—or both simultaneously—in just 15 minutes.
NIBIB selected three winning teams for designs that excel according to four criteria: the significance of the problem being addressed; the impact on clinical care; the innovation of the design; and the ideation process or existence of a working prototype.
Sometimes scientists discover exciting results after spending years searching for an answer to a single question. But sometimes discoveries are made by surprising collaborations and connections—resulting in answers to questions no one would have thought ask.
The winners of National Institutes of Health’s 9th annual Design by Biomedical Undergraduate Teams (DEBUT) challenge developed simple and low-cost diagnostics and treatments for conditions such as tuberculosis, cervical cancer, birth defects, and onchocerciasis (river blindness).