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Funded Projects for Medical Devices

Grant Number Project Title Principal Investigator Institution
1-R21-EB036298-01 Development of potent and safe CRISPR tools for in vivo gene editing using directed evolution Shannon Miller Scripps Research Institute, The
5-R01-EB031124-04 Directed evolution of a sequence-specific targeting technology for therapeutic gene delivery to the human genome. Jesse Owens University of Hawaii at Manoa
1-R21-EB035738-01 Endothelial cell-assisted extracellular vesicle bioengineering for cytoplasmic delivery of therapeutic molecules Clair Crewe Washington University
5-R01-EB032726-04 Engineered BacNav and BacCav for Improved Excitability and Contraction Nenad Bursac Duke University
5-R21-EB033841-02 Engineering and Testing of Biomimetic Stimulators for Therapeutic Applications Michael Kuhns University of Arizona
5-R01-EB035016-02 Engineering human-derived programmable RNA effectors to retune gene expression Bryan Dickinson University of Chicago
1-R01-EB036085-01 Engineering recombinase circuits for cellular diagnostic devices Wilson Wong Boston University (Charles River Campus)
5-R21-EB033121-02 Glia Exclusive Gene Therapy Or Shemesh University of Pittsburgh at Pittsburgh
1-K08-EB036081-01 In vivo enrichment of cell-free DNA to boost sensitivity of circulating nucleic-acid based diagnostics Shervin Tabrizi Massachusetts General Hospital
1-R21-EB033963-01A1 Mitigating the Immunogenicity of Engineered Aav Gene Delivery Vectors by Biomaterial-Driven Immunosuppression Shaoyi Jiang Cornell University