The Interagency Modeling and Analysis Group (IMAG) celebrated its 20th year during the two-day annual IMAG Multiscale Modeling Consortium meeting in late June at the Natcher Conference Center and via virtual attendance. Source: NIH Record. 

A team of Rice University engineers has launched a first of its kind, open-source software that constructs and uses personalized computer models of how individual patients move to optimize treatments for neurologic and orthopedic mobility impairments. Source: Rice University

Established by NIBIB in January, the BETA Center will serve as a hub for expert teams of technology developers at the NIH intramural program and beyond to work together to rapidly address pressing health needs. Source: NIH Catalyst

T cells experience different mechanical signals in different tissues. Researchers have engineered a tissue-mimicking hydrogel model to show that more elastic tissues induce T cells to become effector-like T cells with strong tumor-killing potential, while more viscous tissues induce them to become memory-like T cells. This new concept could help advance adaptive T cell therapies by producing desired patient-specific T cell populations in the dish that could provide stronger effects when infused back into the same patient. Source: Wyss Institute for Biologically Inspired Engineering at Harvard/Science Daily

A first-of-its-kind robotic glove is lending a “hand” and providing hope to piano players who have suffered a disabling stroke. Developed by researchers from Florida Atlantic University’s College of Engineering and Computer Science, the soft robotic hand exoskeleton uses artificial intelligence to improve hand dexterity. Source: Boca Raton Tribune

Researchers have discovered a new combination of drugs that significantly boosts the efficacy of anti-cancer treatments for colorectal cancers implanted in mice. The results also highlight a previously unknown mechanism of DNA repair. Source: National Cancer Institute

A team of researchers has developed a new method for controlling lower limb exoskeletons using deep reinforcement learning. The method enables more robust and natural walking control for users of lower limb exoskeletons. The study, "Robust walking control of a lower limb rehabilitation exoskeleton coupled with a musculoskeletal model via deep reinforcement learning," is available open access. Source: Kessler Foundation/Science Daily

Attaching sugar molecules to proteins can affect protein activities in the cell — and this behavior can be exploited to treat diffuse large B-cell lymphomas (DLBCL), according to a recent study. The finding sets up an unexpected approach to targeted therapy for this aggressive disease. Source: National Cancer Institute

Therapeutic nanocarriers engineered from adult skin cells can curb inflammation and tissue injury in damaged mouse lungs, new research shows, hinting at the promise of a treatment for lungs severely injured by infection or trauma. Source: Ohio State University/Science Daily