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Interferometric Photoactivated Localization Microscope (IPALM)

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Jiji Chen , Ph.D.
Jiji Chen
Staff Scientist

Capable of unsurpassed optical resolution, this system is a clone of the original prototype developed at the Janelia Research Campus, but offers 3 color capability. IPALM combines photoactivated localization microscopy with single-photon, simultaneous multiphase interferometry providing <20 nm resolution in all three dimensions. This microscope is currently located in the Taraska Lab and will move to AIM once the facility is operational.

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IPALM of clathrin in PC12 cells

Figure 1. IPALM of clathrin in PC12 cells