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2024 Design by Biomedical Undergraduate Teams (DEBUT) Challenge Winners

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Program Director
Division of Interdisciplinary Training

Thank you to the all the entrants and congratulations to the 2024 winning teams!

NIBIB-sponsored prizes

"We congratulate all the participants and their mentors on the impressive engineering designs and their passion for addressing compelling healthcare problems. DEBUT demonstrates the power of interdisciplinary teams coming together to deliver solutions to benefit patients.”

 — Bruce Tromberg, Ph.D., NIBIB Director

Hospital monitor displaying patient data under a hand poised to press a button

NIBIB “Steven H. Krosnick” First Prize ($20,000): UroFlo: An automated and intuitive UTI and blood clot prevention device, Rice University, Houston

Anushka Agrawal, Sahana Prasanna, Robert Heeter, Archit Chabbi, Kevin Li, Richard Chan

UroFlo is an adaptive, automated, intuitive continuous bladder irrigation system to improve post-operative assessment of hematuria (blood in the urine). UroFlo incorporates a spectral sensor to quantify hematuria, adjusts inflow rate automatically and quantifies waste bag outflow rate. A web-based, remotely accessible user interface consolidates data and alerts clinical staff to issues, such as abnormal flow rates, severe hematuria or the need to make a bag replacement.

Watch a video from this team

Hands supporting the handle of a transparent prototype ear canal scope

NIBIB Second Prize ($15,000): OCTAVE: Optical coherence tomography and vibrometry endoscope, University of California, Riverside

Christopher Clark, Minh-Huy Tran, Alexis Valencia, Briana Marquez, Sofia Gandarilla 

OCTAVE is an endoscopic optical coherence tomography imaging probe that is capable of high-resolution, real-time, functional imaging of the middle ear structures. OCTAVE addresses a critical challenge in hearing loss detection by providing the capacity to image middle ear structures with high enough resolution to reveal specific sites of damage to the tympanic membrane.

Watch a video from this team

Top part of picture is a blue stretchy material lying flat on a surface and three images below in which a gloved hand is extended to remove a baby doll from plastic abdomen

NIBIB Third Prize ($10,000): Cesarean Delivery Glove, Northwestern University, Evanston, Illinois

Gabriella Desch-Obi, Alexis Chan, Aiden Smires, Priya Dave 

The Cesarean Delivery Glove (CDG) is a cost-effective, reusable device that allows a single operator to safely and effectively resolve impaction of the fetal head within the mother’s pelvis during the cesarean section procedure. The CDG extends an obstetrician’s reach to provide sufficient force for extraction while minimizing risk of trauma to mother and baby.

Watch a video from this team

NIH-sponsored prizes

“For the third consecutive year, NICHD's National Center for Medical Rehabilitation Research has sponsored a significant prize as part of the DEBUT Challenge. Assistive and rehabilitative technologies such as the low-cost, adaptable, bionic knee developed by this year’s winning team can improve the quality of life for people with physical disabilities.” 

— Theresa Hayes Cruz, Ph.D., director, National Center for Medical Rehabilitation Research

Left part shows hands of an iPhone user scanning an intravenous bag and left side shows closeup image of the face of the iPhone

NIH Office of AIDS Research Technologies for HIV/AIDS Prevention and Care Prize ($15,000): Infusion Pump Mobile Application, Loyola University Chicago

Leah Smith, Dhruv Patel, Lauren David, Zhiyin Wu, Esther Wayntraub 

The Infusion Pump Mobile Application integrates seamlessly with the Baxter Novum IQ infusion pump to ensure accurate and efficient drug infusion in the intensive care unit environment. The app provides patient verification, barcode integration, delivery confirmation, real-time infusion progress monitoring, alert and alarm notifications and direct medication order transmission. Intravenous (IV) infusions can potentially be used for HIV treatment, including antiretrovirals and broadly neutralizing antibodies.

Watch a video from this team

An illustration of a vial with a lid alongside a button that inserts into the lid

NIMHD Healthcare Technologies for Low-Resource Settings Prize ($15,000): NanoLIST, Cornell University, Ithaca, New York

Ruchira Hariharan, Ariella Avigad, Francesca Azzarito, Nathan Palamuttam, Kendal Phinney, Aiko Shibata, Viviana Esquivel, Sophia Hertel 

NanoLIST is a rapid, low-cost test kit that utilizes gold nanoparticles to detect when a person’s saliva sample contains an elevated lead concentration. The test kit produces a result within 30 seconds. Its self-contained format is designed so a test can be safely performed without supervision by a clinician and for easy disposal.

Watch a video from this team

A jar containing a fecal sample with an arrow pointing to an analyzer that is under two result indicators

NCI Technologies for Cancer Prevention, Diagnosis, or Treatment Prize ($15,000): ColoTech: A ‘pro-diagnostic’ for the early detection of colorectal dysplastic and cancerous tissue, Stanford University, Palo Alto, California

Gabriel Seir, Shreya Garg, Kelly Lopez-Cid

ColoTech is a novel, cost-effective screening tool for abnormal (dysplastic) cells and could aid in earlier colorectal cancer detection. ColoTech’s highly sensitive approach uses a probe ingested by the patient that changes chemical composition upon contact with abnormal or cancerous tissue and could be an alternative to colonoscopy.

Watch a video from this team

A prosthetic lower leg with a running shoe and image of a person outfitted with the prosthetic and stepping on stairs

National Center for Medical Rehabilitation Research, NICHD Rehabilitative and Assistive Technologies Prize ($15,000): U-Build Bionic Knee: Transfemoral powered prosthetic, University of Utah, Salt Lake City

Duncan Stewart-Jackson, Elise Nielsen, Eleanor Stevens

The U-Build Bionic Knee is a low-cost, powered lower-extremity prosthesis designed to improve mobility and quality of life for individuals with lower-extremity amputation. The device generates assistive power at the knee joint, enabling ambulation on level ground, uneven terrain, and positive-power activities like sit-to-stand movement and stair ascent.

Watch a video from this team

Illustration of a steel pole with hooks for intravenous bags alongside a photo of three people rolling a prototype of the device in a long hallway

NINR Technologies to Empower Nurses in Community Settings Prize ($15,000): IV pole redesign, Virginia Polytechnic Institute and State University, Blacksburg

Sarah Scheerer, Douglas Argueta, Megan Gulian, Devin Donnelly, Utsav Shah

Intravenous (IV) poles are a staple of healthcare operations, but their current design makes visualizing medications difficult. IV Pole Redesign was built in collaboration with nurses and incorporates a tiered and angled hook rake top, an offset pole portion, a spider base, a line organizer, and wheels that improve mobility across threshold transitions.

Watch a video from this team

Plastic tubing connected to the top of a liquid collection bag on a medical fabric surface

NIDDK Kidney Technology Development Prize ($15,000): NephroGuard, Clemson University, South Carolina

Aaron Spearman, Nicholas Stiebler, Calvin Chernyatinskiy, Omar Aguilar, Alexander Bowie 

NephroGuard is a real-time diagnostic device to quickly detect onset of acute kidney injury in patients following cardiac surgery. NephroGuard uses an electrochemical sensor to detect a biomarker that has been shown to detect kidney injury within hours rather than days.

Watch a video from this team

VentureWell-sponsored prizes

Seated man with right leg elevated and engaged with mechanical footrest

VentureWell Venture Prize ($15,000): Knee-sy Does It: Your therapy automation solution, Stevens Institute of Technology, Hoboken, New Jersey

Brandon Sems, Jalen Bailey, Margaret Gibson, Grace Fukazawa  

Knee-sy Does It is a novel stretching device designed to replicate physical therapy treatment at home for patients suffering from knee osteoarthritis or recovering from knee surgery. Knee-sy Does It delivers a combination of dynamic and static stretches in a sequence similar to that which a physical therapist might administer in practice.

Watch a video from this team

Two views of a surgical retractor on a a black background

VentureWell Design Excellence Prize ($5,000): Malleous: A novel suction-retractor instrument to increase efficiency and effectiveness in the operating room, University of Pittsburgh

Ben Leslie, Anna Imran, Rohit Mantena,

Malleous is a surgical instrument combining suction and ribbon retraction tools in one device while maintaining the retractor's malleable and bendable properties. By reducing the need to pause during surgery, the Malleous device reduces surgery duration, which has the potential to increase surgeons’ efficiency and reduce the risk of complications.

Watch a video from this team

Honorable Mentions

CERV: Cervical Dilation Monitor, Washington University in St Louis, Missouri 

Elizabeth Buzbee, Sandy Montgomery, Annika Avula 

CERV aims to replace manual cervical dilation measurements during labor. The device uses an endoscope held in the vaginal canal by a silicone cup to image the cervix and compute dilation.

Watch a video from this team

 

OcuSound: Accessible Glaucoma Monitoring with Acoustic Tonometry, Johns Hopkins University, Baltimore 

Valerie Wong, Benjamin Miller, Ashish Nalla, Hyun Seo Lee, Maria Giannakopoulos, Elliott Leow, Nancy Yan, Ivan-Alexander Kroumov 

OcuSound is a noninvasive, patient-operated tonometer that uses sound waves and the acoustic properties of the eye to measure intraocular pressure, the key metric for monitoring glaucoma and preventing vision loss.

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Bloom Speculum, Clemson University, South Carolina

Vaishnavi Kanduri, Elizabeth Dods, Karen De Guzman, Angeline Chen 

The Bloom Speculum is a 4-blade, expandable vaginal speculum designed to improve visualization during gynecological procedures, such as loop electrosurgical excision procedures (LEEP) to remove precancerous lesions.

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Endovascular Blood Clot Removal Device with a Non-driven Tip, University of California, San Diego 

Nianza Delfin, Kayla Tracy, Angel Castellanos, Javier Guerrero, Michael Casares 

This blood clot removal tool has a non-driven tip to minimize risk of tip breakage. It includes bearings and bushings attached to a memory shape wire with a molded silicone/rubber tip.

Watch a video from this team  

 

Ostomeasure, Purdue University-Main Campus 

Sathveka Sembian, Maya Federle, Nicholas Buffo, Diya Sakhrani, Nikita Rao 

Ostomeasure allows ostomy patients or medical providers to measure the stoma and cut an appropriately-sized hole in the ostomy bag with one integrated device. The bilateral equal measurement system increases accuracy.

Watch a video from this team