Researchers at the Broad Institute of MIT and Harvard and the McGovern Institute for Brain Research at MIT have developed a system that can detect a particular RNA sequence in live cells and produce a protein of interest in response. Using the technology, the team showed how they could identify specific cell types, detect and measure changes in the expression of individual genes, track transcriptional states, and control the production of proteins encoded by synthetic mRNA. Source: Broad Institute of MIT and Harvard/Science Daily

NIBIB Director Bruce Tromberg talked about his love of lasers, the light-speed advances in optics and photonics he’s witnessed and contributed to throughout his career, and the unique role that NIBIB has played in NIH’s COVID-19 response in this interview with NIH MedlinePlus magazine. Source: MedlinePlus Magazine

Kaitlyn Sadtler, Ph.D., who earned an honorary doctorate from UMBC in 2022, presented a GRIT-X talk on immunology and how the body works to heal after injuries. Sadtler is an investigator and chief of the section on immunoengineering at the NIH’s National Institute for Biomedical Imaging and Bioengineering. She shared how her team is working to develop new methods to help modulate the immune response to injury and implantation of medical devices.

Biomedical engineers at Duke University have demonstrated the most effective treatment for pancreatic cancer ever recorded in mouse models. While most mouse trials consider simply halting growth a success, the new treatment completely eliminated tumors in 80% of mice across several model types, including those considered the most difficult to treat. Source: Science Daily/Duke University

Researchers have found that AI models could accurately predict self-reported race in several types of medical images, suggesting that race information could be unknowingly incorporated into image analysis models.

NIBIB Director Bruce J. Tromberg, Ph.D., has been elected to membership in the National Academy of Medicine.

Researchers have developed a low-cost imaging system that can provide quantitative information about how deep within tissue a cancer cell resides. The system can help surgeons distinguish healthy tissue from tumors and could minimize health disparities in low-resource clinical centers. Source: Science Daily/Optica

NIBIB-funded researchers have developed an interlinked tissue chip system that can model four mature organs in their perspective environments simultaneously. These multi-organ tissue chips could represent a new way to evaluate diseases or drugs that affect multiple different tissues.

The National Institutes of Health, through its Blueprint MedTech program, has established two incubator hubs and launched a funding solicitation in support of commercially viable, clinically focused neurotechnology solutions to diagnose and treat disorders of the nervous system.