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New Microscope Can Image, At Once, the Full 3D Orientation & Position of Molecules in Cells

NIBIB in the News
February 24, 2025

Two heads are better than one, as the saying goes, and sometimes two instruments, ingeniously recombined, can accomplish feats that neither could have done on its own. For the first time, a hybrid microscope born at the University of Chicago's Marine Biological Laboratory (MBL), allows scientists to simultaneously image the full 3D orientation and position of an ensemble of molecules, such as labeled proteins inside cells.  Source: Marine Biological Laboratory at the University of Chicago.