Section on Mechanobiology Publications

Biophysical and Molecular mechanisms that control active wetting and tissue fluidification in epithelial tissues.

Marchesi SGuidolin CMassey AELemahieu GLavagnino ZBeznoussenko GVMironov AAGreen BAllievi EMartini EMagni SGhisleni ALomazzi CBenvenuto AFSchertel AParazzoli DMaiuri PSigismund SGauthier NCavalcanti-Adam AECartagena-Rivera AXGiavazzi FScita GDisanza A

Res Sq

2025 Mar 03

Myosin-independent stiffness sensing by fibroblasts is regulated by the viscoelasticity of flowing actin.

Mittal NMichels EBMassey AEQiu YRoyer-Weeden SPSmith BRCartagena-Rivera AXHan SJ

Commun Mater

2024

Mechanical properties of human tumour tissues and their implications for cancer development.

Massey AStewart JSmith CParvini CMcCormick MDo KCartagena-Rivera AX

Nat Rev Phys

2024 Apr

Septins provide microenvironment sensing and cortical actomyosin partitioning in motile amoeboid T lymphocytes.

Zhovmer ASManning ASmith CNguyen APrince OSáez PJMa XTsygankov DCartagena-Rivera AXSingh NASingh RKTabdanov ED

Sci Adv

2024 Jan 05

Atomic force microscopy-mediated mechanobiological profiling of complex human tissues.

Cho DHAguayo SCartagena-Rivera AX

Biomaterials

2023 Dec

Septins Enable T Cell Contact Guidance Amoeboid-Mesenchymal Switch.

Zhovmer ASManning ASmith CWang JMa XTsygankov DDokholyan NVCartagena-Rivera AXSingh RKTabdanov ED

bioRxiv

2023 Sep 27

Combined AAV-mediated gene replacement therapy improves auditory function in a mouse model of human DFNB42 deafness.

Isgrig KCartagena-Rivera AXWang HJGrati MFernandez KAFriedman TBBelyantseva IAChien W

Mol Ther

2023 Sep 06

Frequency-dependent nanomechanical profiling for medical diagnosis.

Solares SDCartagena-Rivera AX

Beilstein J Nanotechnol

2022

Unbalanced bidirectional radial stiffness gradients within the organ of Corti promoted by TRIOBP.

Babahosseini HBelyantseva IAYousaf RTona RHadi SInagaki SWilson EKitajiri SIFrolenkov GIFriedman TBCartagena-Rivera AX

Proc Natl Acad Sci U S A

2022 Jun 28

Stiffening of Circumferential F-Actin Bands Correlates With Regenerative Failure and May Act as a Biomechanical Brake in the Mammalian Inner Ear.

Rudolf MAAndreeva AKim CEDeNovio ACKoshar ANBaker WCartagena-Rivera AXCorwin JT

Front Cell Neurosci

2022

A myosin chaperone, UNC-45A, is a novel regulator of intestinal epithelial barrier integrity and repair.

Lechuga SCartagena-Rivera AXKhan ACrawford BINarayanan VConway DELehtimäki JLappalainen PRieder FLongworth MSIvanov AI

FASEB J

2022 May

Viscoelastic parameterization of human skin cells characterize material behavior at multiple timescales.

Parvini CHCartagena-Rivera AXSolares SD

Commun Biol

2022 Jan 11

Mechanical Counterbalance of Kinesin and Dynein Motors in a Microtubular Network Regulates Cell Mechanics, 3D Architecture, and Mechanosensing.

Zhovmer ASManning ASmith CHayes JBBurnette DTWang JCartagena-Rivera AXDokholyan NVSingh RKTabdanov ED

ACS Nano

2021 Nov 23

Survey of cancer cell anatomy in nonadhesive confinement reveals a role for filamin-A and fascin-1 in leader bleb-based migration.

Adams GLópez MPCartagena-Rivera AXWaterman CM

Mol Biol Cell

2021 Aug 19

Budding epithelial morphogenesis driven by cell-matrix versus cell-cell adhesion.

Wang SMatsumoto KLish SRCartagena-Rivera AXYamada KM

Cell

2021 Jul 08

Engineering T cells to enhance 3D migration through structurally and mechanically complex tumor microenvironments.

Tabdanov EDRodríguez-Merced NJCartagena-Rivera AXPuram VVCallaway MKEnsminger EAPomeroy EJYamamoto KLahr WSWebber BRMoriarity BSZhovmer ASProvenzano PP

Nat Commun

2021 May 14

Myosin II isoforms promote internalization of spatially distinct clathrin-independent endocytosis cargoes through modulation of cortical tension downstream of ROCK2.

Wayt JCartagena-Rivera ADutta DDonaldson JGWaterman CM

Mol Biol Cell

2021 Feb 01

Coupling of β integrins to actin by a mechanosensitive molecular clutch drives complement receptor-mediated phagocytosis.

Jaumouillé VCartagena-Rivera AXWaterman CM

Nat Cell Biol

2019 Nov

TRIOBP-5 sculpts stereocilia rootlets and stiffens supporting cells enabling hearing.

Katsuno TBelyantseva IACartagena-Rivera AXOhta KCrump SMPetralia RSOno KTona RImtiaz ARehman AKiyonari HKaneko MWang YXAbe TIkeya MFenollar-Ferrer CRiordan GPWilson EAFitzgerald TSSegawa KOmori KIto JFrolenkov GIFriedman TBKitajiri SI

JCI Insight

2019 Jun 20

Cochlear outer hair cell horizontal top connectors mediate mature stereocilia bundle mechanics.

Cartagena-Rivera AXLe Gal SRichards KVerpy EChadwick RS

Sci Adv

2019 Feb

Evaluation of the elastic Young's modulus and cytotoxicity variations in fibroblasts exposed to carbon-based nanomaterials.

Pastrana HFCartagena-Rivera AXRaman AÁvila A

J Nanobiotechnology

2019 Feb 23

Mapping heterogeneity of cellular mechanics by multi-harmonic atomic force microscopy.

Efremov YMCartagena-Rivera AXAthamneh AIMSuter DMRaman A