Skip to main content

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

Section on Mechanobiology Publications

Myosin-independent stiffness sensing by fibroblasts is regulated by the viscoelasticity of flowing actin.
Mittal NMichels EBMassey AEQiu YRoyer-Weeden SPSmith BRCartagena-Rivera AXHan SJ
Commun Mater
2024

Mechanical properties of human tumour tissues and their implications for cancer development.
Massey AStewart JSmith CParvini CMcCormick MDo KCartagena-Rivera AX
Nat Rev Phys
2024 Apr

Septins provide microenvironment sensing and cortical actomyosin partitioning in motile amoeboid T lymphocytes.
Zhovmer ASManning ASmith CNguyen APrince OSáez PJMa XTsygankov DCartagena-Rivera AXSingh NASingh RKTabdanov ED
Sci Adv
2024 Jan 05

Atomic force microscopy-mediated mechanobiological profiling of complex human tissues.
Cho DHAguayo SCartagena-Rivera AX
Biomaterials
2023 Dec

Septins Enable T Cell Contact Guidance Amoeboid-Mesenchymal Switch.
Zhovmer ASManning ASmith CWang JMa XTsygankov DDokholyan NVCartagena-Rivera AXSingh RKTabdanov ED
bioRxiv
2023 Sep 27

Combined AAV-mediated gene replacement therapy improves auditory function in a mouse model of human DFNB42 deafness.
Isgrig KCartagena-Rivera AXWang HJGrati MFernandez KAFriedman TBBelyantseva IAChien W
Mol Ther
2023 Sep 06

Frequency-dependent nanomechanical profiling for medical diagnosis.
Solares SDCartagena-Rivera AX
Beilstein J Nanotechnol
2022

Unbalanced bidirectional radial stiffness gradients within the organ of Corti promoted by TRIOBP.
Babahosseini HBelyantseva IAYousaf RTona RHadi SInagaki SWilson EKitajiri SIFrolenkov GIFriedman TBCartagena-Rivera AX
Proc Natl Acad Sci U S A
2022 Jun 28

Stiffening of Circumferential F-Actin Bands Correlates With Regenerative Failure and May Act as a Biomechanical Brake in the Mammalian Inner Ear.
Rudolf MAAndreeva AKim CEDeNovio ACKoshar ANBaker WCartagena-Rivera AXCorwin JT
Front Cell Neurosci
2022

A myosin chaperone, UNC-45A, is a novel regulator of intestinal epithelial barrier integrity and repair.
Lechuga SCartagena-Rivera AXKhan ACrawford BINarayanan VConway DELehtimäki JLappalainen PRieder FLongworth MSIvanov AI
FASEB J
2022 May

Viscoelastic parameterization of human skin cells characterize material behavior at multiple timescales.
Parvini CHCartagena-Rivera AXSolares SD
Commun Biol
2022 Jan 11

Mechanical Counterbalance of Kinesin and Dynein Motors in a Microtubular Network Regulates Cell Mechanics, 3D Architecture, and Mechanosensing.
Zhovmer ASManning ASmith CHayes JBBurnette DTWang JCartagena-Rivera AXDokholyan NVSingh RKTabdanov ED
ACS Nano
2021 Nov 23

Survey of cancer cell anatomy in nonadhesive confinement reveals a role for filamin-A and fascin-1 in leader bleb-based migration.
Adams GLópez MPCartagena-Rivera AXWaterman CM
Mol Biol Cell
2021 Aug 19

Budding epithelial morphogenesis driven by cell-matrix versus cell-cell adhesion.
Wang SMatsumoto KLish SRCartagena-Rivera AXYamada KM
Cell
2021 Jul 08

Engineering T cells to enhance 3D migration through structurally and mechanically complex tumor microenvironments.
Tabdanov EDRodríguez-Merced NJCartagena-Rivera AXPuram VVCallaway MKEnsminger EAPomeroy EJYamamoto KLahr WSWebber BRMoriarity BSZhovmer ASProvenzano PP
Nat Commun
2021 May 14

Myosin II isoforms promote internalization of spatially distinct clathrin-independent endocytosis cargoes through modulation of cortical tension downstream of ROCK2.
Wayt JCartagena-Rivera ADutta DDonaldson JGWaterman CM
Mol Biol Cell
2021 Feb 01

Coupling of β integrins to actin by a mechanosensitive molecular clutch drives complement receptor-mediated phagocytosis.
Jaumouillé VCartagena-Rivera AXWaterman CM
Nat Cell Biol
2019 Nov

TRIOBP-5 sculpts stereocilia rootlets and stiffens supporting cells enabling hearing.
Katsuno TBelyantseva IACartagena-Rivera AXOhta KCrump SMPetralia RSOno KTona RImtiaz ARehman AKiyonari HKaneko MWang YXAbe TIkeya MFenollar-Ferrer CRiordan GPWilson EAFitzgerald TSSegawa KOmori KIto JFrolenkov GIFriedman TBKitajiri SI
JCI Insight
2019 Jun 20

Cochlear outer hair cell horizontal top connectors mediate mature stereocilia bundle mechanics.
Cartagena-Rivera AXLe Gal SRichards KVerpy EChadwick RS
Sci Adv
2019 Feb

Evaluation of the elastic Young's modulus and cytotoxicity variations in fibroblasts exposed to carbon-based nanomaterials.
Pastrana HFCartagena-Rivera AXRaman AÁvila A
J Nanobiotechnology
2019 Feb 23

Mapping heterogeneity of cellular mechanics by multi-harmonic atomic force microscopy.
Efremov YMCartagena-Rivera AXAthamneh AIMSuter DMRaman A
Nat Protoc
2018 Oct

c-Src activity is differentially required by cancer cell motility modes.
Logue JSCartagena-Rivera AXChadwick RS
Oncogene
2018 Apr

MARCKS-related protein regulates cytoskeletal organization at cell-cell and cell-substrate contacts in epithelial cells.
Van Itallie CMTietgens AJAponte AGucek MCartagena-Rivera AXChadwick RSAnderson JM
J Cell Sci
2018 Feb 02

Actomyosin Cortical Mechanical Properties in Nonadherent Cells Determined by Atomic Force Microscopy.
Cartagena-Rivera AXLogue JSWaterman CMChadwick RS
Biophys J
2016 Jun 07