Explore more about: Regenerative Medicine

NIBIB-funded researchers are working to make bladder surgeries better, tackling the issue from two vantage points: improving bladder function using a biodegradable construct that facilitates tissue regeneration, and enhancing patient monitoring by developing an implantable bladder sensor.

Diabetic wounds are slow-healing, potentially life-threatening complications with limited treatment options. But a two-step, nanomaterial-based strategy may open doors to better care.

Researchers at The Pennsylvania State University have developed a new synergistic approach to revascularization that combines a new framework made from granular hydrogels with micropuncture, a surgical technique. Their preclinical method could rapidly grow organized blood vessels in live rats.

Introducing medical devices — commonly made of materials such as titanium, silicone, or collagen — into our bodies can elicit a host of different immune responses. While some responses can harm our bodies, others can help heal them. A new study fills in a critical piece of the puzzle.

Tissue engineering research has uncovered that a skin cell type could be a new therapeutic target to accelerate the healing of burns and possibly other wounds.

Osteoarthritis – a painful condition that results from the deterioration of the cartilage in our joints – affects millions of people worldwide. To combat this issue, NIBIB-funded researchers are developing an implantable, biodegradable film that helps to regenerate the native cartilage at the site of damage. Their study, performed in rabbits, could be an initial, important step in the establishment of a new treatment.

NIBIB-funded researchers have found a way to model the human neuromuscular junction by growing these synapses in a lab, which could accelerate novel treatments for neuromuscular diseases.

A University of Arkansas professor has received a four-year, $1.6 million grant from the National Institutes of Health to develop non-invasive, real-time “optical biopsies” of chronic skin wounds.

The new technique is capable of printing the models 10-50 times faster than the industry standard—in minutes instead of hours— a major step in the quest to create 3D-printed replacement organs.

The technique used in this preclinical study could aid tissue regeneration following severe accidents, surgical resections, or progressive muscle loss due to age or genetic disease.